ea0037ep766 | Pituitary: clinical | ECE2015
Olarescu Nicoleta Cristina
, Jorgensen Anders P
, Heck Ansgar
, Normann Kjersti R
, Godang Kristin
, Bollerslev Jens
Context: Angiopoietin-like protein 4 (Angptl4) is a protein involved in lipolysis, that is regulated by non-esterified free fatty acids (FFA). GH promotes lipolysis and increases circulating FFA. Hypothesis: GH increases circulating Angptl4 levels by modulating its expression and secretion from fat and muscle. Angptl4 might be of metabolic relevance for the insulin resistance associated with GH/IGF1 excess or deficiency.Objective: To evaluate Angptl4 in ...